Functional Neuroimaging Laboratoryof the Department of Psychiatryof the Joan and Sanford I. Weill Medical Collegeof Cornell UniversityHome Overview Research Team Projects Methods Development Education Publications Links |
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Selected Publications Silbersweig D, Stern E, Frith CD, Cahill C, Schnorr L, Grootoonk S, Spinks T, Clark J, Frackowiak R, Jones T. Detection of thirty-second cognitive activations in single subjects with positron emission tomography: a new low dose H215O regional cerebral blood flow three-dimensional imaging technique. J Cereb Blood Flow Metab 13: 617-629, 1993 Silbersweig D, Stern E, Schnorr L, Frith CD, Ashburner J, Cahill C, Frackowiak R, Jones T. Imaging transient, randomly-occurring neuropsychological events in single subjects with positron emission tomography: an event-related countrate correlational analysis. J Cereb Blood Flow Metab, 14: 771-782, 1994. Silbersweig DA, Stern E, Frith C, Cahill C, Holmes A, Grootoonk S, Seaward J, McKenna P, Chua SE, Schnorr L, Jones T, Frackowiak RSJ. A functional neuroanatomy of hallucinations in schizophrenia. Nature, 378: 176-179, 1995. Reinsel R, Veselis RA, Feshchenko VA, Di Resta GR, Mawlawi O, Beatty B, Silbersweig D, Stern E, Blasberg R, Macapinlac H, Finn R, Goldsmith S, Larson S. Target detection and the prefrontal cortex: a PET scan study of the P300 event-related potential. Ann NY Acad Sci, 769:393-397, 1995. Engelien A, Silbersweig D, Stern E, Huber W, Frith C, Frackowiak R. The functional anatomy of recovery from auditory agnosia - A PET study of sound categorization in a neurologic patient and normal controls. Brain, 118: 1395-1409, 1995. Eidelberg D, Ishikawa T, Moeller JR, Dhawan V, Spetsieris P, Silbersweig D, Stern E, Fazzini E, Dogali M, Beric A. The regional metabolic correlates of surgical outcome following unilateral ventral pallidotomy for Parkinson's disease. Annals of Neurology, 39: 450-459, 1996. Jones T, Silbersweig DA, Stern E, Schnorr L, Seaward J, Clark JC, Lammertsma AA, Grootoonk S. The development of in-vivo tracer methods to obtain new information about human disease: a study of the hallucinating brain. Eur J Nucl Med , 23: 332-335, 1996. Silbersweig DA and Stern E. Functional neuroimaging of hallucinations in schizophrenia: toward an integration of bottom-up and top-down approaches. Molecular Psychiatry, 1: 367-375, 1996. Isenberg N, Silbersweig D, Engelien A, Emmerich S, Malavade K, Beattie B, Leon A, Stern E. Linguistic threat activates the human amygdala. Proc Natl Acad Sci USA, 96:10456-9, 1999. Blumberg H, Stern E, Ricketts S, Martinez D, De Asis J, White T, Epstein J, Isenberg N, McBride A, Kemperman I, Emmerich S, Dhawan V, Eidelberg D, Kocsis J, Silbersweig D. Rostral and orbital prefrontal cortex dysfunction in the manic state of bipolar disorder. Am J Psychiatry, 156:1986-1988, 1999. Bremner JD, Innis RB, White T, Fujita M, Silbersweig D, Goddard A, Staib L, Stern E, Cappiello A, Woods S, Baldwin R, Charney DS. SPECT [I-123] Iomazenil measurement of the benzodiazepine receptor in panic disorder. Biol Psychiatry, 47: 96-106, 2000. Engelien A, Huber W, Silbersweig D, Stern E, Frith C, Doring W, Thron A, Frackowiak R. The neural correlates of ‘deaf-hearing’ in man: conscious sensory awareness enabled by attentional modulation. Brain, 123:532-45, 2000. Yang Y, Engelien A, Engelien W, Xu S, Stern E, Silbersweig DA. A Silent Event-Related Functional MRI Technique for Brain Activation Studies without Interference of Scanner Acoustic Noise. Magnetic Resonance in Medicine, 43:185-90,2000. Stern E, Silbersweig DA, Chee K-Y, Holmes A, Robertson M, Trimble M, Frith CD, Frackowiak RSJ, Dolan R. A functional neuroanatomy of tics in Tourette’s syndrome. Arch Gen Psychiatry, 57: 741-748, 2000. Yang Y, Engelien W, Pan H, Xu S, Silbersweig DA, Stern E. A CBF-based event-related brain activation paradigm: Characterization of impulse-response function and comparison to BOLD. Neuroimage, 12, 287-297, 2000. Yang
Y, Engelien W, Xu S, Silbersweig DA, Stern E.
Transit time, trailing time and cerebral blood flow during brain
activation: measurement using multislice, pulsed spin-labeling perfusion
imaging, Magnetic Resonance in Medicine, 44:680-685, 2000. Blumberg H, Stern E, Martinez D, Ricketts S, De Asis J, White T, Epstein J, McBride A, Eidelberg D, Kocsis J, Silbersweig D. Increased anterior cingulate and caudate activity in bipolar mania. Biological Psychiatry 48:1045-1052, 2000. De Asis J, Stern E, Alexopoulos GS, Pan H, Van Gorp W, Blumberg H, Kalayam B, Eidelberg D, Silbersweig DA. Decreased hippocampal and anterior cingulate activation in geriatric depression. American Journal of Psychiatry 158:1321, 2001. Gu H, Engelien W, Feng H, Silbersweig DA, Stern E, Yang Y. Mapping transient, randomly occurring neuropsychological events using independent component analysis. Neuroimage, 14: 1432-1443, 2001. Yang
Y, Gu H, Zhan W, Xu S, Silbersweig DA, Stern E. Simultaneous perfusion and BOLD
imaging using reversed spiral
scanning at
3T: characterization of functional contrasts and susceptibility artifacts. Magn.
Reson. Med., 48:278-89, 2002. Engelien A, Yang Y, Engelien W, Zonana J, Stern E, Silbersweig DA. Physiological Mapping of Human Auditory Cortices with a Silent Event-Related fMRI Technique. Neuroimage, 16:944-953, 2002. Gu H, Feng H, Zhan W, Silbersweig DA, Stern E, Yang Y. Single-shot interleaved Z-Shim EPI with optimized compensation for signal losses due to susceptibility-induced field inhomogeneity at 3T. NeuroImage 17:1358-64, 2002. Zhan W, Gu H, Silbersweig DA, Stern E, Yang Y. Inversion profiles of adiabatic inversion pulses for flowing spins: the effects on labeling efficiency and labeling accuracy in perfusion imaging with pulsed arterial spin-labeling. Magn. Reson. Imag., 20:487-94, 2002. Zhan W, Gu H, Xu S, Silbersweig DA, Stern E, Yang Y. Circular spectrum mapping for intravoxel fiber structures based on high angular resolution apparent diffusion coefficients. Magn. Reson. Med., 49: 1077-88, 2003. Beutel M, Stern E, Silbersweig DA. The emerging dialogue between psychoanalysis and neuroscience: neuroimaging perspectives. J Am Psychoanalytic Assn. 51: 773-801, 2003. Tuscher O, Silbersweig D, Smith T, Pan H, Beutel M, Zonana J, Erbesh V, Weisholtz D, Stern E, A. Engelien. Processing of environmental sounds in schizophrenic patients: disordered recognition and lack of semantic specificity, Schizophrenia Research, 73: 291-295, 2005. Protopopescu X, Tuescher O, Pan H, Goldstein M, Cloitre M, Gorman J, Ledoux JE, Engelien W, Silbersweig D, Stern E. Differential time-courses and specificity of amygdala activation in PTSD subjects and normal controls. Biological Psychiatry, 57: 464-473, 2005. Yang Y, Gu H, Silberweig DA, Stern E. Simultaneous perfusion and BOLD measurements using single-shot interleaved Z-shim echo-planar imaging (SSIZS-EPI). Magnetic Resonance in Medicine, 53: 1207-1211, 2005. Sigman
M, Pan H, Yang Y, Stern E, Silbersweig D, Gilbert C.
Large scale reorganization of
activity in the visual pathway with training on object recognition. Neuron
46: 823-35, 2005. Butler T, Pan H,
Epstein J, Protopopescu X, Tuescher O, Goldstein M, Cloitre M, Yang Y, Phelps E,
Gorman J, Ledoux J, Stern E, Silbersweig D.
Fear-related activity in subgenual anterior cingulate differs between men
and women. Neuroreport 16: 1233-1236, 2005. Protopopescu X,
Pan H, Altemus M, Tuescher O, Polanecsky M, McEwen B, Silbersweig D, Stern E. Orbitofrontal cortex activity related to emotional processing
changes across the menstrual cycle. Proc
Natl Acad Sci USA (PNAS),
102(44): 16060-5, 2005. Voyer D, Butler T, Cordero J, Brake B, Silbersweig D, Stern E, & Imperato-McGinley J. The Relation between Computerized and Paper-and-Pencil Mental Rotation Tasks: A Validation Study. Journal of Clinical and Experimental Neuropsychology (in press). Engelien A, Tuescher O, Hermans W, Isenberg N, Eidelberg D, Frith C, Stern E, Silbersweig D. Functional neuroanatomy of non-verbal semantic sound processing in humans. J Neural Transmission, 113: 599–608, 2006. Epstein J, Pan H, Kocsis JH, Yang Y, Butler T, Chusid J, Hochberg H, Murrough J, Strohmayer E, Stern E, Silbersweig DA. Lack of ventral striatal response to positive stimuli in depressed versus normal subjects. American Journal of Psychiatry 163(10): 1784-1790, 2006. Protopopescu X, Pan H, Tuescher O, Cloitre M, Goldstein M, Engelien A, Yang Y, Gorman J, LeDoux J, Silbersweig D, Stern E. Increased brainstem volume in panic disorder: a voxel-based morphometric study. Neuroreport, 17(4): 361-363, 2006.
Butler T, Imperato-McGinley J, Pan H, Voyer D, Cordero J, Stern E, Silbersweig DA. Sex differences in mental rotation: Top down versus bottom up processing. NeuroImage 32: 445-456, 2006.
Goldstein M, Brendel G, Tuescher O, Pan H, Epstein J, Beutel M, Yang Y, Thomas K, Posner M, Levy L, Clarkin J, Kernberg O, Stern E, Silbersweig D. Neural substrates of the interaction of emotional stimulus processing and motor inhibitory control: An emotional linguistic go/no-go fMRI study. NeuroImage 36(3): 1026-1040, 2007.
Other Publications Silbersweig
D. Neurology
for Psychiatrists, in Core Readings in Psychiatry, Sacks MH, Sledge WH,
Warren C, eds. Washington, American Psychiatric Press, Inc, 1995, pp 435-447 Friston
KJ, Frith CD, Fletcher P, Silbersweig DA, Cahill C, Dolan R, Liddle P,
Frackowiak RSJ, Herold S. Abnormal Fronto-Temporal Interactions in
Schizophrenia, in Biology of Schizophrenia and Affective Disease, Watson
SJ, ed. New York, ARNMD Series, vol. 73, Raven Press, 1996. Kemperman
I, Silbersweig D, Stern E, Russ M.
Brain Imaging and Personality Disorders, in Brain Imaging in Clinical
Psychiatry, Krishnan KRR and Doraiswamy PM, eds. New York, Marcel Dekker,
Inc., 1997. Silbersweig
DA, Stern E. Symptom
Localization in Neuropsychiatry: a Functional Neuroimaging Approach, in Frontiers
of Neurology: a Symposium in Honor of Fred Plum, Reis DJ and Posner JB, eds.
New York, Annals of The New York Academy of Sciences, 1997, pp 410-420 Stern
E, Silbersweig D.
Neural Mechanisms Underlying Hallucinations in Schizophrenia:
The Role of Abnormal Fronto-Temporal Interactions, in The Pathogenesis
of Schizophrenia: an Experimental Psychopathology Perspective,
Lenzenweger MF and Dworkin RH, eds.
Washington, D.C., American Psychological Association, 1998, pp 235-246. Epstein
J, Stern E, Silbersweig DA, Mesolimbic activity associated with psychosis in
schizophrenia: symptom-specific PET studies, in Advancing from the ventral
striatum to the extended amygdala: implications for neuropsychiatry and drug
abuse, McGinty JF, ed.
New York, Annals of the New York Academy of Sciences, 1999, 877: 562-574. Stern
E, Silbersweig DA.
Symptom capture as a strategy for methodologic development and
pathophysiologic investigation in functional neuropsychiatric imaging, in Strategies
in psychiatric neuroimaging: clinical and research applications.
D. Dougherty and S Rauch, eds.
American Psychiatric Press, 2001. Alexopoulos
GS, Bruce ML, Silbersweig D, Stern E, Kalayam B.
Vascular Depression: A New View of Late-Onset Depression, Dialogues in
Clinical Neuroscience, in press. Stern
E, Silbersweig DA.
Advances in functional neuroimaging methodology for the study of brain
systems underlying human neuropsychological function and dysfunction.
Journal of Clinical and Experimental Neuropsychology, special issue:
Neuropsychology and Functional Neuroimaging: Convergence, Advances and New
Directions, Silbersweig DA and Stern E, eds, 2001. Engelien
A, Stern E, Silbersweig D.
Functional
neuroimaging of human central auditory processing in normal subjects and
patients with neurological and neuropsychiatric disorders. Journal of
Clinical and Experimental Neuropsychology, in special issue: Neuropsychology and
Functional Neuroimaging: Convergence, Advances and New Directions,
Silbersweig DA and Stern E, eds, 2001. Silbersweig
D, Stern E. Neuropsychology
and Functional Neuroimaging: Convergence, Advances and New Directions. Journal
of Clinical and Experimental Neuropsychology, in special issue: Neuropsychology
and Functional Neuroimaging: Convergence, Advances and New Directions,
Silbersweig DA and Stern E, eds, 2001. Epstein
J, Stern E, Silbersweig D.
Hallucinations: exploring mechanisms from psychology to neurobiology,
in Encyclopedia of the Human Brain, Ramachandran, ed, Elsevier
Science, 2002. Engelien
A, Stern E, Isenberg N, Engelien W, Frith C, Silbersweig D.
The parahippocampal region and auditory-mnemonic processing. Annals of
the New York Academy of Sciences, 911:477-85, 2000.
Epstein
J, Stern E, Silbersweig D. Neuropsychiatry at the millenium: the potential for
mind/brain integration through emerging interdisciplinary research strategies. Clinical
Neuroscience Research: 1, 10-18, 2001. Silbersweig
D. Toward a neurobiology of psychiatry at the millennium. Clinical
Neuroscience Research: 1, 9, 2001. Epstein
J, Isenberg N, Stern E, Silbersweig D. Toward
a neuroanatomical understanding of psychiatric illness: the role of functional
imaging, in Defining Psychopathology in the 21st Century (DSM-V
and Beyond), Helzer J and Hudziak J, eds, American Psychiatric Publishing,
2002. Epstein
J, Stern E, Silbersweig D.
Hallucinations: A functional neuroanatomic perspective.
Concise
Corsini Encyclopedia of Psychology and Behavioral Science, 2004. Posner
M, Rothbart M, Vizueta N, Thomas K, Levy K, Fossella J, Silbersweig D, Stern E,
Clarkin J, Kernberg O.
An approach to the psychobiology of personality disorders.
Development and Psychopathology, 15:1093-106, 2003. DeAsis
J, Silbersweig D, Pan H, Young R, Stern E.
Neuroimaging Studies of fronto-limbic dysfunction in geriatric
depression. Clinical Neurosciences.
2: 324-330, 2003. Butler
T, Stern E, Silbersweig D. Functional
Neuroimaging of Tourette Syndrome: Advances and Future Directions.
In Advances in Neurology: 4th International Scientific
Symposium on Tourette Syndrome (in press). Brendel
G and Silbersweig D. Defining the
Neurocircuitry of Borderline Personality Disorder: Functional Neuroimaging
Approaches. Development and
Psychopathology, (in press). Neuropsychology
and Functional Neuroimaging: Convergence, Advances and New Directions,
Silbersweig DA and Stern E, eds, SWETS and Zeitlinger Publishers, The
Netherlands, 2001. |
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